+33 (0)1 76 54 08 64
66 avenue des Champs-Élysées
75008 Paris – France
Authors: Peggy Provent, Elodie Marie-Dit-Chatel, Jordan Longin, Stanislas Urbain, François Scherninski, Cyril Berthet
Abstract: Fluorescent dyes have been used in medical diagnostics for over 50 years. The emergence of new fluorescent imaging technology in support of surgery and the need for increased sensitivity and precision have driven the search for novel fluorescent molecules.
Orthotopic patient-derived xenograft (PDX) pancreatic tumor models provide a closely related human tumor within organ-specific tumor microenvironment, which was well suited to the evaluation of the tissue specificity of two novel fluorescent compounds, developed by Proimaging, with specific tumor uptake.
A scratch assay is a widely used laboratory technique to study the ability of cells to migrate and close a “scratch” or “wound” made in a monolayer of cultured cells. This assay is valuable for studying cell migration, a fundamental process in tissue repair, development, and disease progression…
Labeling dyes can be employed to visualize mitochondrial dynamics in living cells. By using specific fluorescent dyes mitochondria within cells can be selectively stained and observed under fluorescence microscopy…