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LBL-Dye M715

Additional information

Application

Cell membrane labeling

Max absorption

690 nm

Max emission

715 nm

Shipping condition

Room Temperature for up to 3 weeks

Storage condition

Store 12 months after receival under -15°C and protect from light

Molecular weight

∼ 810

Solubility

– PBS Buffer (pH 7.4) + 1% Tween 80
– DMSO

LBL-Dye M715

LBL-Dye M715 is a near-infrared (NIR) cell membrane labeling dye and mitochondrial tracker for preclinical in-vitro or in-vivo studies.

LBL-Dye M715 is a lipophilic fluorescent dye that binds to membranes with a 715 nm emission wavelength with a high fluorescence yield.

The fluorophore part of the dye molecule binds at the aqueous interface of the membrane and the alkyl tail enters the lipid layer.

The fluorescence of the dye bound on membranes is first quenched at high dye concentration then released after dilution. This property makes this dye useful for membrane fusion assays.

LBL-Dye M715 replaces Octadecyl Rhodamine B Chloride (R18) and offers the advantage to be used in near-infrared (NIR).

Product for Research Use Only. Not for Human Use.

Confocal imaging of H28 living cells labeled with LBL-Dye M715 
Confocal imaging of H28 living cells labeled with LBL-Dye M715

Product citations :

Optimization of Advanced Live-Cell Imaging through Red/Near-Infrared Dye Labeling and Fluorescence Lifetime-Based Strategies
Int. J. Mol. Sci. 2021, 22(20), 11092; https://doi.org/10.3390/ijms222011092

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