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Cell membrane labeling
Room Temperature for up to 3 weeks
Store 12 months after receival under -15°C and protect from light
– PBS Buffer (pH 7.4) +1% Tween 80
LBL-Dye M717 is a cell membrane labeling dye and mitochondrial tracker in near-infrared for preclinical in-vitro or in-vivo studies.
LBL-Dye M717 is more amphiphilic than Octadecyl Rhodamine B Chloride (R18) and binds to membranes with a 717 nm emission wavelength with a high fluorescence yield.
The fluorophore part of the dye molecule binds at the aqueous interface of the membrane and the alkyl tail enters the lipid layer.
The fluorescence of the dye bound on membranes is first quenched at high dye concentration then released after dilution. This property makes this dye useful for membrane fusion assays.
Product for Research Use Only. Not for Human Use.
Confocal imaging of H28 living cells labeled with LBL-Dye M717
Product citations :
Optimization of Advanced Live-Cell Imaging through Red/Near-Infrared Dye Labeling and Fluorescence Lifetime-Based Strategies
Int. J. Mol. Sci. 2021, 22(20), 11092; https://doi.org/10.3390/ijms222011092
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